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Anti-IgG2 Antibody

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Absea Biotechnology
068812D06
Details
Description: Mouse monoclonal (KT138) antibody to IgG2
Category: Primary Antibodies
Applications: ELISA
Host: Mouse
Clonality: Monoclonal
Clone: KT138
Isotype: IgG1
Conjugate: Unconjugated
UniProt: P01859
Antigen: IgG2
Antigen Species: Human
Uniprot Protein Name: Ig gamma-2 chain C region

Target (Information from UniProt)
Function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location: Secreted. Cell membrane.

Product Code - 068812D06
Size Price Quantity
100µg £178
200µg £259
1mg £682

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