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Anti-IgG2 Antibody

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Absea Biotechnology
068812D06
Overview
Name: Anti-IgG2 Antibody
Description: Mouse monoclonal (KT138) antibody to IgG2.
Applications: ELISA
Reactivity: Human
Immunogen: Human IgG2.
Host: Mouse
Clonality: Monoclonal
Clone: KT138
Isotype: IgG1
Conjugate: Unconjugated
Purification: IgG is purified through a Protein A column.
Concentration: 1 mg/ml in PBS containing 0.09% sodium azide as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target (Information from UniProt)
Function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location: Secreted. Cell membrane.
UniProt: P01859
Synonyms: Ig gamma-2 chain C region Antibody
IGHG2 Antibody
immunoglobulin Gm2 Antibody
immunoglobulin heavy constant gamma 2 (G2m marker) Antibody
immunoglobulin heavy constant, gamma 2 Antibody

Images
ELISA - Anti-IgG2 Antibody from Absea Biotechnology (068812D06) - Antibody Supply Service
ELISA using plates coated with human antibodies with various isotypes.

Product Code - 068812D06
Size Price Quantity
100µg £178
200µg £259
1mg £682

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