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Anti-IgG4 Antibody (HRP)

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Absea Biotechnology
068709G12H
Overview
Name: Anti-IgG4 Antibody (HRP)
Description: Mouse monoclonal (KT130) antibody to IgG4 (HRP).
Applications: ELISA
Reactivity: Human
Immunogen: Human IgG4.
Host: Mouse
Clonality: Monoclonal
Clone: KT130
Isotype: IgG1
Conjugate: HRP
Purification: IgG is purified through a Protein A column and labelled with horseradish peroxidase.
Concentration: 1 mg/ml in PBS containing 0.01% thimerosal as a preservative.
Storage: 4 °C for 1 month, -20 °C or -80°C in aliquots. Avoid repeated freeze/thaw cycles.

Target (Information from UniProt)
Function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Cellular Location: Secreted. Cell membrane.
UniProt: P01861
Synonyms: Ig gamma 4 chain C region Antibody
IGHG4 Antibody
Immunoglobulin heavy constant gamma 4 (G4m marker) Antibody
MGC117419 Antibody

Images
ELISA - Anti-IgG4 Antibody (HRP) from Absea Biotechnology (068709G12H) - Antibody Supply Service
ELISA using plates coated with human IgG antibodies.

Product Code - 068709G12H
Size Price Quantity
100µg £186
200µg £273
1mg £730

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