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Anti-PIGR Antibody

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Absea Biotechnology
000007C01
Details
Description: Rat monoclonal (7C1) antibody to PIGR (Polymeric immunoglobulin receptor)
Category: Primary Antibodies
Applications: IHC, WB
Host: Rat
Clonality: Monoclonal
Clone: 7C1
Isotype: IgG1
Conjugate: Unconjugated
UniProt: P01833
Gene ID: 5284
Antigen: PIGR (Polymeric immunoglobulin receptor)
Antigen Species: Human, Mouse
Uniprot Protein Name: Polymeric immunoglobulin receptor (short name: PIgR)
Uniprot Gene Name: PIGR

Target (Information from UniProt)
Function: This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
Post-Translational Modification: N-glycosylation is not necessary for Ig binding.
Cellular Location: Cell membrane.

Product Citations

Wang R et al. Human Fcalpha/muR and pIgR distribute differently in intestinal tissues. Biochem. Biophys. Res. Commun. 381(2): 148-52 (2009)

Wang R et al. Human Fcalpha/muR and pIgR distribute differently in intestinal tissues. Biochem. Biophys. Res. Commun. 381(2): 148-52 (2009)


Product Code - 000007C01
Size Price Quantity
100µg £186
200µg £273
1mg £730

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